Search results for "Therapy related"

showing 3 items of 3 documents

Biology and management of therapy-related acute promyelocytic leukemia.

2013

Therapy-related acute promyelocytic leukemia (t-APL) has been increasingly reported after exposure to cytotoxic and/or immunosuppressive agents given for prior malignancies or autoimmune diseases. t-APL represents both a model for better understanding human leukemogenesis and an interesting therapeutic subset which requires specific adaptations for optimal management.We discuss here potential risk factors for t-APL development and the main biologic and clinical characteristics of t-APL as compared to de-novo APL.In addition, we review therapeutic results obtained in patients with t-APL receiving conventional retinoic acid and chemotherapy and discuss new treatment opportunities with minimal…

Acute promyelocytic leukemiaAdultMaleCancer ResearchRetinoic acidAntineoplastic AgentsTretinoinAcuteArsenicalschemistry.chemical_compoundArsenic TrioxideLeukemia Promyelocytic Acuteimmune system diseasesRisk FactorsNeoplasmsCytotoxic T cellMedicineHumansArsenic trioxideneoplasmsAdult; Antineoplastic Agents; Arsenicals; Early Diagnosis; Female; Humans; Leukemia Promyelocytic Acute; Male; Middle Aged; Neoplasms Second Primary; Oxides; Retrospective Studies; Risk Factors; TretinoinRetrospective StudiesPromyelocyticTherapy relatedLeukemiabusiness.industryNeoplasms Second PrimaryOxidesMiddle Agedmedicine.diseaseSecond PrimaryEarly DiagnosisOncologychemistryCancer researchFemalebusinessSettore MED/15 - Malattie del SangueCurrent opinion in oncology
researchProduct

A Decision-support Algorithm for Self-management of Anticoagulation Therapy Used in a Smartphone Application

2019

Warfarin for anticoagulation therapy is used by patients with specific cardiovascular diseases to control the ability of blood clotting. Traditional ways for self-management of the therapy are based on paper forms and procedures. This paper presents an algorithm developed for the smartphone application “Warfarin Guide”, which is a computer-assisted decision-support system used to help patients with self-management of their anticoagulation therapy related to International Normalized Ratio (INR) values. The algorithm was based on clinical guidelines for Warfarin therapy and it was adapted for the software application to address challenges with regular INR checks and adjustments for temporary …

Decision support systemSelf-managementTherapy related020205 medical informaticsBlood clottingComputer sciencebusiness.industryWarfarinWarfarin therapy02 engineering and technologySmartphone applicationVDP::Matematikk og Naturvitenskap: 400::Informasjons- og kommunikasjonsvitenskap: 420Health informatics03 medical and health sciences0302 clinical medicine0202 electrical engineering electronic engineering information engineeringmedicineeHealthheterocyclic compoundscardiovascular diseases030212 general & internal medicinebusinessAlgorithmmedicine.drug2019 IEEE Symposium on Computers and Communications (ISCC)
researchProduct

THERapy–Related InterACTion (THER-I-ACT) in Rehabilitation—Instrument Development and Inter-Rater Reliability

2021

Objective: To develop an instrument for the observation of therapeutic communication interactions during rehabilitation sessions and test its inter-rater reliability.Methods: The new instrument THER-I-ACT (THERapy–related Inter-ACTion) has been designed to assess both the frequency and timing of therapeutic interactions in the thematic fields information provision, feedback, other motivational interaction, and bonding. For this inter-rater reliability study, a sample of stroke survivors received arm rehabilitation as either arm ability training, arm basis training, or mirror therapy, or neglect training as individually indicated. Therapy sessions were video-recorded (one for each participan…

medicine.medical_specialtyIntraclass correlationmedicine.medical_treatmentmedia_common.quotation_subjectassessmentinteractionfeedbackratingbehavioral disciplines and activitiesNeglectrehabilitationPhysical medicine and rehabilitationmedicineRC346-429Reliability (statistics)media_commontherapyRehabilitationTherapy relatedbehaviorallianceBrief Research ReportTest (assessment)Inter-rater reliabilityNeurologyObservational studyNeurology (clinical)Neurology. Diseases of the nervous systemPsychologyFrontiers in Neurology
researchProduct